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HSA / FSA ELIGIBLE
MONEY BACK GUARANTEE
FREE USA SHIPPING
HSA / FSA ELIGIBLE
MONEY BACK GUARANTEE
FREE USA SHIPPING
Ingredients:
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Enzyme supplements work by making direct contact with food in the stomach. Capsules dissolve separately, limiting how much enzyme reaches FODMAPs before they ferment in the small intestine and cause symptoms. FODZYME®'s powder format ensures enzymes are pre-mixed with food, maximizing contact time.
In a peer-reviewed study (Castro Ochoa et al., Gastro Hep Advances, 2023), this approach degraded up to 90% of fructans within 30 minutes. A 2026 clinical study (Kaye et al., Gastro Hep Advances) found 78% of participants reported improvement in bloating from FODMAP ingestion after 4 weeks. FODZYME® is the only FODMAP enzyme supplement certified low-FODMAP by both Monash University and FODMAP Friendly.
Allow hot foods to cool slightly before applying (below 140 °F / 60 °C).
Mix directly or apply evenly on meals. It’s tasteless.
Can’t mix? Sprinkle and chew with first bite.
Double dose if extra sensitive or for large meals.
Fructan Hydrolase: One of FODZYME’s core innovations, this enzyme helps break down fructans and inulin found in foods like garlic, onions, and wheat.
Alpha-galactosidase: Targets GOS (galacto-oligosaccharides) present in beans and legumes, aiding digestion.
Lactase: Simplifies the digestion of lactose, commonly found in dairy products.
Dextrin: Sourced from non-GMO maize/corn, used to stabilize the enzymes, ensuring they remain effective throughout digestion.
Contains no GMOs, gluten, milk, egg, casein, soy, or artificial colors or flavors.
FODZYME comes in two serving formats. The Home Kit provides 750 mg (0.75 g) per serving, which is our standard serving for meals at home, where you typically have more visibility into ingredients. The On-the-Go Kit stick packs provide 1 g per serving to help cover the hidden FODMAPs more common in restaurant or takeaway meals. The Anywhere Bundle includes both the Home Kit and the On-the-Go Kit.
Serving size is not based on body weight or age. Instead, it depends on the size of the meal and its FODMAP content. Our servings are designed to work well for most users. Start with one serving and adjust based on the meal and your experience. For larger meals or meals especially high in FODMAPs, consider using 2 servings.
Allow hot foods to cool slightly before applying (below 140 °F / 60 °C).
Mix directly or apply evenly on meals. It’s tasteless.
Can’t mix? Sprinkle and chew with first bite.
Double dose if extra sensitive or for large meals.
Meals Made Painless
90%
78%
73%
FODZYME® is supported by two peer-reviewed publications in Gastro Hep Advances. In a SHIME® study (Castro Ochoa et al., 2023), it degraded 90% of fructans within 30 minutes while preserving short-chain fatty acid (SCFA) and butyrate production — unlike a strict low-FODMAP diet, which depletes SCFAs critical for colonic microbiome health. In an IRB-approved clinical cohort study independently analyzed at SUNY Downstate (Kaye et al., 2026), 78% of participants reported improvement in bloating and flatulence from FODMAP ingestion after 4 weeks, with significant improvements in quality of life and mental well-being (all P<.01).
Mix directly or apply evenly on meals.
Double dosage when feasting. Chew well. Enjoy.
Our current formula effectively breaks down the FODMAPs fructan (e.g., garlic, onion, wheat, ...), GOS (e.g., legumes, nuts), and lactose (e.g., dairy products). We are actively developing a solution for polyols (e.g., apple, avocado, mushrooms) such as sorbitol and mannitol.
** FODZYME® significantly reduces fructan (a FODMAP) in wheat, barley and rye products, not gluten. Fructan is often the real trigger in individuals with non-celiac gluten sensitivity.
Learn moreFODZYME® can help unlock a long list of healthy, nutritious and delicious foods like,
Wheat bread **
Onion
Garlic
Banana
Wheat pasta **
Artichoke
Cream cheese
Ice cream
Dairy milk
Brussels sprouts
Lentils
Cashews
Scallions
Leek
Beetroot
And many more delicious and nutritious foods
** FODZYME® significantly reduces fructan (a FODMAP) in wheat, barley and rye products, not gluten. Fructan is often the real trigger in individuals with non-celiac gluten sensitivity.
Learn more
FODZYME®
Home Kit
Your everyday essential. A jar built for the kitchen counter.
FODZYME®
On-The-Go Kit
Our most powerful dose yet. 33% more enzyme activity — ideal for dining out or travel.
FODZYME® is formulated as a tasteless powder to ensure maximum contact between its digestive enzymes and FODMAP-containing foods, allowing for more effective breakdown of FODMAPs during digestion. Unlike capsules, the powder mixes directly with food, optimizing enzyme performance and supporting better digestive relief.
Our formulation consists of clinically and scientifically studied microbial enzymes characterized at both academic institutions, and research partners.
ENZYME BLEND (32MG PER G)
Our fructan hydrolase is the first ever enzyme to target fructans like inulin, fructo-oligosaccharides (FOS), and levan.
Our alpha-galactosidase enzyme can effectively break down the galacto-oligosaccharides (GOS) or galactans (“O” in FODMAPs).
Our lactase enzyme (also called β-D-galactosidase) can break down lactose (the “D” in FODMAPs).
Other ingredients: dextrin (from non-GMO corn)
Contains no GMOs, gluten, milk, egg, casein, soy, or artificial colors or flavors.
Soy-free
Egg-free
Non-GMO
Casein-free
Gluten Free
No artificial flavors
Dairy-free
Kosher
Vegan
FDA-Registered Facility
Soy-free
Egg-free
Non-GMO
Casein-free
Gluten Free
No artificial flavors
Dairy-free
Kosher
Vegan
FDA-Registered Facility
Engineered specifically to break down FODMAPs
Patent-pending formula with first-ever fructan-targeting enzyme.
Powder form for superior efficacy
Powder format allows the enzymes to mix directly with food.
Scientifically validated
Backed by peer-reviewed scientific publications, demonstrating its effectiveness.
Rigorously tested
Third-party tested for enzyme activity, allergens, and contaminants.
Certified low-FODMAP
Founded by an IBS sufferer, FODZYME® is a tasteless enzyme powder that breaks down FODMAPs — fermentable carbohydrates that trigger bloating, gas, diarrhea, constipation, and abdominal pain. It contains three active enzymes: fructan hydrolase (the first commercially available enzyme targeting fructans in garlic, onion, and wheat), alpha-galactosidase (for GOS in beans and legumes), and lactase (for lactose in dairy). FODZYME® is mixed directly with food before eating, manufactured in the USA, and independently certified low-FODMAP by Monash University.
Contains no GMOs, gluten, milk, egg, casein, soy, or artificial colors or flavors.
Yes, FODZYME® is:
FODZYME® targets three primary FODMAP groups—fructans, galacto-oligosaccharides (GOS), and lactose—which are common triggers for digestive discomfort. Its enzyme blend works on foods like garlic, onions, wheat, beans, lentils, dairy products, and certain vegetables, breaking these FODMAPs into easily digestible sugars.
Key Food Groups Supported and Example Foods:
Most digestive enzyme supplements contain proteases, lipases, and amylases that target proteins, fats, and starches — not FODMAPs, which are the primary dietary triggers of digestive symptoms like bloating, gas, and pain. FODZYME® is the first enzyme supplement specifically formulated to break down FODMAPs. Its proprietary fructan hydrolase targets fructans found in garlic, onion, and wheat, while alpha-galactosidase targets GOS in beans and legumes, and lactase targets lactose in dairy.
FODZYME® is a powder rather than a capsule, ensuring direct enzyme-food contact during digestion. In a peer-reviewed study, this approach degraded up to 90% of fructans within 30 minutes (Castro Ochoa et al., Gastro Hep Advances, 2023). A 2026 clinical cohort study found 78% of participants reported improvement in bloating from FODMAP ingestion after 4 weeks (Kaye et al., Gastro Hep Advances, 2026; P<.01). It is the only enzyme supplement certified low-FODMAP by both Monash University and FODMAP Friendly.
FODZYME® begins breaking down FODMAPs immediately upon contact with food. In a peer-reviewed study (Castro Ochoa et al., Gastro Hep Advances, 2023), it degraded up to 90% of fructans within 30 minutes under simulated gastric conditions. This rapid action breaks down FODMAPs in the stomach and upper small intestine — before they reach the colon where bacterial fermentation causes bloating and gas.
Most users notice the absence of their usual symptoms 4–8 hours after a FODMAP-rich meal, consistent with normal gastrointestinal transit time. In an IRB-approved clinical study (Kaye et al., Gastro Hep Advances, 2026), 78% of participants reported improvement in bloating and flatulence from FODMAP ingestion after 4 weeks (P<.01).
Yes, FODZYME®is designed for safe daily use. Its enzymes are naturally occurring and work specifically on FODMAPs without interfering with normal digestion or nutrient absorption. Regular use can help manage symptoms and expand dietary choices for those following a low FODMAP diet.
FODZYME® is generally considered safe to use alongside most medications, as its enzymes work specifically on FODMAPs in the digestive tract. However, it’s always a good idea to consult your healthcare provider or pharmacist before starting any new supplement—especially if you’re taking prescription medications.
Individual responses can vary. If you notice any unusual symptoms or changes in medication effectiveness, discontinue use and consult your healthcare provider immediately.
No. FODZYME® is a digestive enzyme supplement, not a cure for Irritable Bowel Syndrome (IBS) or any medical condition. It works by breaking down specific FODMAP carbohydrates in food during digestion, which may reduce symptoms triggered by those foods — including bloating, gas, and abdominal pain. FODZYME® does not address the underlying causes of IBS.
If you have been diagnosed with IBS or suspect you have a digestive disorder, consult a gastroenterologist or registered dietitian. FODZYME® can be used alongside medical treatment and the low-FODMAP diet as directed by your healthcare provider.
FODZYME®’s powdered format mixes directly with your food for instant action on FODMAPs—no waiting for a capsule to dissolve. This allows for:
FODZYME®’s enzymes work on your food without entering your body, making it a low-risk option. However, because studies on pregnant or breastfeeding women are limited for ethical reasons, there’s no concrete evidence it’s unsafe—but it’s best to consult your physician before use.
Keep in mind that a low FODMAP diet isn’t generally advised during pregnancy due to potential nutritional restrictions, so always prioritize a nutrient-rich diet. Rest assured that all ingredients are GRAS-certified and undergo rigorous third-party testing for safety and quality.
A FODZYME® subscription provides flexibility and savings by offering:
You also have the option to subscribe to both. Subscribers receive a $15 discount on all orders, along with the ability to adjust delivery frequency, skip shipments, or cancel anytime.
If you are not satisfied with your purchase for any reason, you may request a refund within 30 days of delivery of your first order. You’ll receive a full refund for the product cost—less shipping, VAT, and duties—no questions asked.
If you are on a FODZYME® subscription plan, you may reschedule, pause, or cancel anytime.
Please note: Refunds apply to your first order only, not any subsequent shipments.
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